The bark of Rhamnus purshiana (cascara sagrada) contains laxative anthranoid derivatives, which occur primarily in various laxative herbs (such as aloe, cascara sagrada, medicinal rhubarb, and senna) in the form of free anthraquinones, anthrones, dianthrones, and/or O- and C-glycosides derived from these substances
-31%
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The plant is indigenous to the western part of North America and is also cultivated in Canada and eastern Africa. Cascara is used for the relief of constipation and hemorrhoids and as a rectoanal postoperative treatment.
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