Smilax glabra extract is derived from the rhizome of the Smilax glabra plant, also known as China root or sarsaparilla, and is used in traditional medicine and as a food ingredient for its various pharmacological properties. Modern research indicates that S. glabra extract has anti-infective, anti-cancer, anti-inflammatory, and antioxidant activities due to its rich content of flavonoids, phenolic acids, and other compounds like astilbin. The extract is used in functional foods and herbal formulas to support detoxification, liver health, and immune function, and studies have shown its potential to inhibit cancer cell growth and migration.
Traditional and Modern Uses
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Traditional Medicine:S. glabra has a long history of use as a food and folk medicine in China, Sri Lanka, and other Asian countries. It was traditionally used to treat conditions such as syphilis, skin diseases like eczema and itching, and various internal ailments.
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Modern Applications:The extract is a common ingredient in functional foods, herbal teas, and health products. Modern research supports its traditional uses, demonstrating potential benefits for treating inflammatory conditions, cancer, and liver-related diseases.
Key Components and Properties
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Flavonoids and Phenolics:S. glabra is rich in flavonoids and phenolic compounds, which are responsible for many of its biological activities.
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Active Compounds:Notable compounds include astilbin, which possesses antibacterial, anti-inflammatory, and antioxidant properties, and taxifolin.
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Pharmacological Effects:Studies have shown S. glabra extract to have broad pharmacological activities, including:
- Anti-infective: Inhibits certain bacteria.
- Anti-cancer: Can induce apoptosis (programmed cell death) and inhibit cancer cell migration and invasion.
- Anti-inflammatory: Exhibits anti-inflammatory effects, helping to alleviate inflammatory conditions.
- Antioxidant: Scavenges free radicals and protects against oxidative stress.
- Cardioprotective and Hepatoprotective: Offers protection for the cardiovascular system and liver.
- Immuno-modulatory: Modulates the immune system.
- Anti-infective: Inhibits certain bacteria.
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