Picrorhiza kurroa extract is a herbal extract from the roots and rhizomes of the Picrorhiza kurroa plant, a high-altitude Himalayan herb used in traditional medicine for its hepatoprotective (liver-protective), antioxidant, and anti-inflammatory properties. The active compounds, primarily picrosides (Picroside I and II), are used in formulations to treat liver damage, asthma, and various other ailments, though it is classified as an endangered plant due to overcollection.
Key Properties and Uses
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Hepatoprotective:Picrorhiza kurroa extract and its components, like picrosides, are known to protect the liver from damage caused by toxins, viruses (such as hepatitis C), and lifestyle factors.
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Antioxidant and Anti-inflammatory:The extract’s antioxidant activity helps reduce oxidative damage, while its anti-inflammatory effects can alleviate inflammation and reduce symptoms of conditions like asthma.
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Anticancer Potential:Research suggests the extract exhibits anticancer properties by inducing apoptosis (programmed cell death) in cancer cells and regulating cell cycle checkpoints.
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Immune Modulation:It can activate immune responses and protect against harmful agents, making it a potential immunomodulator.
Active Components
- Picrosides: These are the primary active constituents, including Picroside I and Picroside II, responsible for many of the plant’s therapeutic effects.
- Cucurbitacins and Phenolic Components: Other bioactive compounds also contribute to the plant’s medicinal value.
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