Gymnema sylvestre extract has been associated with several potential health benefits, particularly related to blood sugar control, appetite suppression, and cholesterol levels. The herb is known in Ayurveda as “gurmar,” meaning “sugar destroyer,” because chewing its leaves temporarily suppresses the taste of sweetness.
Blood sugar and diabetes management
- Reduces sugar absorption: The primary active compounds in Gymnema sylvestre, called gymnemic acids, have a molecular structure similar to glucose. This allows them to bind to sweet taste receptors on the tongue and receptors in the intestinal lining, blocking sugar molecules from being absorbed.
- Improves insulin function: The extract may stimulate insulin secretion from the pancreas’s beta cells and promote the regeneration of these cells in some cases.
- Lowers blood sugar: Multiple clinical studies have found that supplementation can lead to a significant reduction in fasting and postprandial (after-meal) blood glucose levels in adults with type 2 diabetes.
- Reduces sugar cravings: By temporarily blocking sweet taste receptors, gymnemic acids make sugary foods less appealing, which can help reduce cravings.
- Supports weight loss: By curbing sugar intake and preventing the absorption of carbohydrates, the extract can aid in weight management. Studies in animal models have also shown a suppression of body weight gain.
Heart health and cholesterol- Lowers cholesterol and triglycerides: A systematic review published in Phytotherapy Research found that supplementation significantly decreased levels of triglycerides, total cholesterol, and low-density lipoprotein (LDL) cholesterol.
- Helps prevent plaque formation: The extract’s bioactive compounds help break down fat and prevent the formation of plaque in arteries.
Other reported benefits- Antioxidant and anti-inflammatory properties: The extract is rich in antioxidants like tannins and saponins that combat oxidative stress and inflammation, potentially lowering the risk of chronic disease.
Appetite control and weight management

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