Commiphora mukul extract, also known as guggul, is an herbal supplement derived from the resin of the mukul myrrh tree. It has been used for over 2,000 years in traditional Ayurvedic medicine for various conditions, including heart disease, obesity, and arthritis. Its primary active compounds are guggulsterones.
Potential health benefits
- Cholesterol management: Extracts of C. mukul have demonstrated cholesterol-lowering effects by decreasing “bad” LDL cholesterol and triglycerides, while increasing “good” HDL cholesterol.
- Anti-inflammatory properties: The extract’s guggulsterones are known for their anti-inflammatory activity. They can help reduce joint pain, inflammation, and stiffness, making them potentially beneficial for conditions like osteoarthritis and rheumatoid arthritis.
- Thyroid health: Some research indicates that guggul extract can stimulate thyroid function, specifically by enhancing the conversion of thyroid hormone T4 to the more active T3. This may aid in weight management and metabolic function.
- Weight management: By supporting thyroid activity and promoting lipid metabolism, guggul can assist with healthy weight management. It helps in the reduction of fat and the elimination of toxins.

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