Description
Spermidine is a natural polyamine that has many uses, including:
Cellular homeostasis: Spermidine helps maintain cellular homeostasis and metabolism.
Anti-aging: Spermidine can help protect against aging-related issues, such as cognitive decline and neurodegeneration. It can also help prolong lifespan in mice, flies, and nematodes.
Cancer: Spermidine can help regulate cellular apoptosis and autophagy, and can modulate the expression of enzymes like monoamine oxidase (MAO) and SSAT. When combined with anticancer chemotherapeutics, spermidine can help inhibit tumor growth.
Molecular biology: Spermidine is used in in vitro molecular biology reactions, such as in vitro transcription and translation.
DNA transfer: Spermidine is used in electroporation to transfer DNA into cells, and to precipitate DNA onto microprojectiles for gene gun bombardment.
Fertility: Spermidine may play a role in male and female fertility.
Inflammation: Spermidine can help control excessive inflammation, such as in dry eye syndrome.
Blood pressure: Spermidine has been correlated with lower blood pressure in humans
Clinical studies suggest that 1-6 mg of spermidine per day is an optimal supplement
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